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Accessories-Brain in a bottle.jpg
Bound accessory
Blank image2.jpg     Requires:
Level 11
Procs-Brainblast.png  Proc: Brainblast level 2
Procs-Paranoia.png  Proc: Paranoia level 1



I've got the brain of a four year old.
I'll bet he was glad to be rid of it.

— Groucho Marx


The brain-in-a-bottle is an accessory.


The brain-in-a-bottle accessory increases your chance of hitting an opponent by 10%.


You must be at least level 11 to craft and use the brain-in-a-bottle accessory.


The brain-in-a-bottle has the following procs associated with it:

  • Procs-Brainblast.png  Brainblast: The brainblast proc is an offensive buff that gives a chance to deal additional psychic damage against an opponent. Brainblast is a level 2 proc on a brain-in-a-bottle accessory.
  • Procs-Paranoia.png  Paranoia: The paranoia proc is an offensive proc that causes the opponent to take extra damage from psychic sources. Paranoia is a level 1 proc on a brain-in-a-bottle accessory.


The brain-in-a-bottle can be combined with one or more of the following items to form the set descent into madness:

Belt Insanity belt
Boots Path of madness
Glyph Glyph of madness
Hand armor Grip of madness
Head armor Mask of madness

When two or more set items are used together, your entire set-up receives an additional bonus. See the descent into madness page or the sets page for more information about those bonuses.



You must craft the brain-in-a-bottle accessory with the assistance of the chaos agent, the merchant in Dark oblivion.

Crafting materials

Collect the following items to craft the brain-in-a-bottle:


You cannot trade or give a brain-in-a-bottle to another player.


You cannot disenchant a brain-in-a-bottle.


  • 9 May 2011: The brain-in-a-bottle accessory was added to Chronicles of Blood.

See also

You might also be interested in looking at:

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